HuagongsheHuagongshe Chemistry Print Report · For research reference only
Formaldehyde → 3-(Morpholinomethyl)-2-(methoxycarbonylamino)-6-(phenylthio) imidazo [1,2-a] pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Formaldehyde | HCID 712 | — |
| Reactant | Morpholine | HCID 8083 | — |
| Reactant | Methyl [6-(phenylsulfanyl)imidazo[1,2-a]pyridin-2-yl]carbamate | HCID 12414300 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Product | 3-(Morpholinomethyl)-2-(methoxycarbonylamino)-6-(phenylthio) imidazo [1,2-a] pyridine | HCID 53632248 | — |
Reaction Steps
From the reaction of 0.75 g. of 2-(methoxycarbonylamino)-6-(phenylthio) imidazo [1,2-a] pyridine and 0.83 ml. acetic acid, 18 ml. of 37% formaldehyde and 0.216 g. of morpholine, following the procedure of Example 8, there is obtained 3-(morpholinomethyl)-2-(methoxycarbonylamino)-6-(phenylthio) imidazo [1,2-a] pyridine m.p. 158°-182° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04250174 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-0318106ef1c744ce8382caa5781dac7f |
| Source note | uspto-grants-1981_02 |