Hydrogen Bromide → HCID 178419740, compound

HRID 1413442Notes

Reaction equation

HRID 1413442 reaction equation
C[O:2][C:3]1[CH:4]=[C:5]([N:13]=[C:14]2[NH:18][CH2:17][CH2:16][NH:15]2)[CH:6]=[C:7]([O:11]C)[C:8]=1[O:9]C.[BrH:19]>>[BrH:19].[OH:11][C:7]1[CH:6]=[C:5]([N:13]=[C:14]2[NH:15][CH2:16][CH2:17][NH:18]2)[CH:4]=[C:3]([OH:2])[C:8]=1[OH:9]

Participants

3

Reactant 2

HCID 260Hydrogen BromideHCID 178493079HCID 178493079, compound

Product 1

HCID 178419740HCID 178419740, compoundYield 78.6%

Procedure

A mixture of 8 gm (0.032 mol) of 2-(3,4,5-trimethoxy-phenylimino)-imidazolidine base and 150 ml of 48% of hydrobromic acid was refluced for 5 hours on an oil bath. Thereafter, the reaction mixture was evaporated in vacuo to half its original volume and allowed to stand overnight in the refrigerator. The amorphous precipitate which had formed was isolated and dried, yielding 7.3 gm (78.6% of theory) of 2-(3,4,5-trihydroxy-phenylimino)-imidazolidine hydrobromide, m.p. 204°-206° C., Rf -value 0.3 in mobile phase 75 parts sec.butanol, 15 parts formic acid, 10 parts water. Carrier: silicagel, visualization; potassium iodoplatinate.

Workup

  1. customThereafter, the reaction mixture was evaporated in vacuo to half its original volume
  2. waitto stand overnight in the refrigerator
  3. customThe amorphous precipitate which had formed
  4. customwas isolated
  5. customdried

Sources & evidence

ORD record
ord-8266bc95747d43ea9da1c72cb45b8920
Source dataset
uspto-grants-1981_02
Patent number
US04250186

Reaction notes

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