HuagongsheHuagongshe Chemistry Print Report · For research reference only
Propargylamine → 1-Nitro-2-(propynylamino)-2-{2-[(2-pyridyl)methylthio]ethylamino)ethylene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Propargylamine | HCID 239041 | — |
| Reactant | 1-Nitro-2-methylthio-2-[2-(2-pyridylmethylthio)ethylamino]ethylene | HCID 70570329 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 1-Nitro-2-(propynylamino)-2-{2-[(2-pyridyl)methylthio]ethylamino)ethylene | HCID 70570126 | — |
Reaction Steps
A mixture of the product of Step A (2.0 g; 7.03 mmoles) and propargylamine (3.44 g; 62.5 mmoles) in acetonitrile (30 ml) was stirred and heated to reflux temperature under a positive pressure of nitrogen for 1.5 hours then stirred at ambient temperature for 42 hours. The reaction mixture was filtered and the product collected. Recrystallization from acetonitrile gave the title compound; mp 147°-148°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04250316 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-6b26959808754933adba1ad524efa929 |
| Source note | uspto-grants-1981_02 |