反应详情

In the same manner as in Example 1(b) the 22.1 grams of 2-(3-chlorophenoxy) nicotinic acid was combined with 13.0 grams (0.1 mole) thionyl chloride, 0.5 grams triethylamine hydrochloride and 200 milliliters chloroform to produce 23.2 grams (98.3% of theoretical yield) of 2-(3-chlorophenoxy)nicotinoyl chloride, m.p. 72°-74° C.