反应详情

To a solution of 5.0 g. cyclopropyldiphenylsulfonium tetrafluoroborate in 30 ml. water at 90°-95° C. is added 50 ml. of hot solution of potassium acetate (obtained by mixing 26.6 g. acetic acid with 24.0 g. potassium hydroxide). The reaction mixture is stirred well and maintained at 90°-95° C. for several minutes and allowed to cool to room temperature gradually. The reaction mixture is then filtered free of any solids; the aqueous filtrate extracted several times with methylene chloride, the combined methylene chloride extracts are dried over sodium sulphate, filtered and evaporated i.v. to dryness. From the residue is obtained on trituration with ether the title product, as an oil.

1. temperaturemaintained at 90°-95° C. for several minutes
2. filtrationThe reaction mixture is then filtered free of any solids
3. extractionthe aqueous filtrate extracted several times with methylene chloride
4. dry with materialthe combined methylene chloride extracts are dried over sodium sulphate
5. filtrationfiltered
6. customevaporated i.v