HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Aminophenol → HCID 20290821, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Aminophenol | HCID 5801 | — |
| Reactant | 2-Propanone, 1,1,3,3-tetrafluoro- | HCID 67758 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | HCID 20290821 | HCID 20290821 | — |
Reaction Steps
A mixture of 2-amino-hydroxybenzene, toluene and sym-tetrafluoroacetone can be heated in a Hastelloy® bomb. The solvent can be removed by evaporation and the residual material can be purified by chromatography on silica gel to give 4-amino[2,2-difluoro-1-hydroxy-1-(difluoromethyl)ethyl]-3-hydroxybenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04251534 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-bd3244e06be84743a1531bec8eda11ee |
| Source note | uspto-grants-1981_02 |