HCID 20290922, compound → HCID 10451707, compound

HRID 1413836Notes

Reaction equation

HRID 1413836 reaction equation
[Cl-].[NH:2]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:4]([CH2:11][CH2:12][CH2:13][CH2:14][N+:15]2[CH:20]=[CH:19][C:18]([C:21]3[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=3)=[CH:17][CH:16]=2)=[CH:3]1>CO.[Pt]>[C:21]1([CH:18]2[CH2:17][CH2:16][N:15]([CH2:14][CH2:13][CH2:12][CH2:11][C:4]3[C:5]4[C:10](=[CH:9][CH:8]=[CH:7][CH:6]=4)[NH:2][CH:3]=3)[CH2:20][CH2:19]2)[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1

Participants

4

Reactant 1

HCID 20290922HCID 20290922, compound

Product 1

HCID 10451707HCID 10451707, compound

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 887MethanolSolvent

Procedure

1 g of 1-[4-(3-indolyl)-butyl]-4-phenylpyridinium chloride is dissolved in 25 ml of methanol and hydrogenated on 0.1 g of platinum at 25° and normal pressure until the reaction has ceased; the reaction mixture is filtered; the filtrate is evaporated; and, after customary working up, 3-[4-(4-phenyl-1-piperidyl)-butyl]-indole is obtained; hydrochloride, m.p. 213°-215°.

Workup

  1. filtrationthe reaction mixture is filtered
  2. customthe filtrate is evaporated

Sources & evidence

ORD record
ord-674af33de17a47f1a1c208185171237b
Source dataset
uspto-grants-1981_02
Patent number
US04251538

Reaction notes

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