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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1413845Generated: October 31, 2026

Tert-Butylamine → 3-Methyl-5-[2-(2-hydroxy-3-tert.-butylaminopropoxy)-styryl]-isoxazole

https://huagongshe.com/reaction/1413845

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTert-ButylamineHCID 6385—
Reactant3-Methyl-5-[2-(2,3-epoxypropoxy)-styryl]-isoxazoleHCID 54495624—
Product3-Methyl-5-[2-(2-hydroxy-3-tert.-butylaminopropoxy)-styryl]-isoxazoleHCID 194469—

Reaction Steps

This compound is obtained by the method described for Example 1 from 5.0 g (0.019 mole) of 3-methyl-5-[2-(2,3-epoxypropoxy)-styryl]-isoxazole and 1.56 g (0.2 mole) of tert.-butylamine. 3.1 g (48% of theory) of colorless crystals, melting point 83°-85° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04251539
Source datasetuspto-grants-1981_02
ORD IDord-143c489c31c845d6834ac5dcd0bb5091
Source noteuspto-grants-1981_02