Tert-Butylamine → 3-Methyl-5-[2-(2-hydroxy-3-tert.-butylaminopropoxy)-styryl]-isoxazole

HRID 1413845Notes

Reaction equation

HRID 1413845 reaction equation
[CH3:1][C:2]1[CH:6]=[C:5]([CH:7]=[CH:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[O:15][CH2:16][CH:17]2[O:19][CH2:18]2)[O:4][N:3]=1.[C:20]([NH2:24])([CH3:23])([CH3:22])[CH3:21]>>[CH3:1][C:2]1[CH:6]=[C:5]([CH:7]=[CH:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=2[O:15][CH2:16][CH:17]([OH:19])[CH2:18][NH:24][C:20]([CH3:23])([CH3:22])[CH3:21])[O:4][N:3]=1

Participants

3

Reactant 2

HCID 6385Tert-ButylamineHCID 544956243-Methyl-5-[2-(2,3-epoxypropoxy)-styryl]-isoxazole

Product 1

HCID 1944693-Methyl-5-[2-(2-hydroxy-3-tert.-butylaminopropoxy)-styryl]-isoxazole

Procedure

This compound is obtained by the method described for Example 1 from 5.0 g (0.019 mole) of 3-methyl-5-[2-(2,3-epoxypropoxy)-styryl]-isoxazole and 1.56 g (0.2 mole) of tert.-butylamine. 3.1 g (48% of theory) of colorless crystals, melting point 83°-85° C.

Workup

  1. customThis compound is obtained by the method

Sources & evidence

ORD record
ord-143c489c31c845d6834ac5dcd0bb5091
Source dataset
uspto-grants-1981_02
Patent number
US04251539

Reaction notes

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