HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclopropylamine → 3-Isopropyl-5-[2-(2-hydroxy-3-cyclopropylaminopropoxy)-styryl]-isoxazole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Reactant | 3-Isopropyl-5-[2-(2,3-epoxypropoxy)-styryl]-isoxazole | HCID 54459054 | — |
| Product | 3-Isopropyl-5-[2-(2-hydroxy-3-cyclopropylaminopropoxy)-styryl]-isoxazole | HCID 53884109 | — |
Reaction Steps
7 g (0.025 mole) of 3-isopropyl-5-[2-(2,3-epoxypropoxy)-styryl]-isoxazole and 3 g (0.05 mole) of cyclopropylamine are reacted by the method described in Example 5. 3.0 g (30% of theory) of colorless crystals are obtained as the fumurate. Melting point 148°-152° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04251539 |
| Source dataset | uspto-grants-1981_02 |
| ORD ID | ord-54f5162ebc9e46818ce63167d55584e0 |
| Source note | uspto-grants-1981_02 |