Acetone → Ammonia
Reaction equation
[NH2:1][C:2]([CH3:6])([CH3:5])[C:3]#[N:4].CC(C)=[O:9]>>[CH3:5][C:2]([CH3:6])([OH:9])[C:3]#[N:4].[CH:2]#[N:1].[NH3:1].[C-:2]#[N:1].[NH4+:1]Participants
Procedure
The present invention provides a process for producing 2,2'-azobis(2-methylpropionitrile) by subjecting 2-amino-2-methylpropionitrile obtained by the reaction between acetone cyanohydrin and ammonia, or acetone, hydrogen cyanide and ammonia, or acetone and ammonium cyanide to oxidative coupling using a metal hypochlorite, which comprises (1) subjecting the crude 2-amino-2-methylpropionitrile obtained by said reaction to distillation under reduced pressure while maintaining the temperature of the heat transfer medium at 0° to 50° C. and the pressure at 400 mmHg or less, whereby a low-boiling fraction comprising ammonia is removed, to obtain a purified 2-amino-2-methylpropionitrile product having an ammonia content of not more than 1.5% by weight, (2) contacting the purified product with an aqueous metal hypochlorite solution at a temperature of not more than about 30° C., the pH of the hypochlorite solution being about 10 to 13.5, and the concentration of the hypochlorite being 5% by weight or less based on the weight of the reaction mixture, and then (3) treating the resulting aqueous suspension of 2,2'-azobis(2-methylpropionitrile) with at least one reducing agent selected from the group consisting of nitrites, sulfites, bisulfites, pyrosulfites, thiosulfates, sulfur dioxide, nitrogen oxide, oxalic acid, formaldehyde, hydrazine, hydrogen peroxide and hydroxylamine.
Sources & evidence
- ORD record
- ord-53528a2c5a014d9c8e7284d3f2db5ef3
- Source dataset
- uspto-grants-1981_02
- Patent number
- US04252717
Reaction notes
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