Acetone → Ammonia
Reaction equation
[NH2:1][C:2]([CH3:6])([CH3:5])[C:3]#[N:4].CC(C)=[O:9]>>[CH3:5][C:2]([CH3:6])([OH:9])[C:3]#[N:4].[CH:2]#[N:1].[NH3:1].[C-:2]#[N:1].[NH4+:1]Participants
Procedure
A process for producing 2,2'-azobis(2-methylpropionitrile) by subjecting 2-amino-2-methylpropionitrile obtained by the reaction between acetone cyanohydrin and ammonia, or acetone, hydrogen cyanide and ammonia, or acetone and ammonium cyanide to oxidative coupling using a metal hypochlorite, which comprises (1) subjecting the crude 2-amino-2-methylpropionitrile obtained by said reaction to distillation at a temperature of the heat transfer medium of 0° to 50° C. and a pressure of 400 mmHg or less to obtain a purified 2-amino-2-methylpropionitrile product having an ammonia content of 1.5% by weight or less, (2) contacting the purified product with an aqueous metal hypochlorite solution at a temperature of not more than about 30° C., the pH of the hypochlorite solution being about 10 to 13.5 and the concentration of the metal hypochlorite being 5% by weight or less based on the weight of the reaction mixture, and then (3) treating the resulting aqueous suspension of 2,2'-azobis(2-methylpropionitrile) with at least one reducing agent selected from the group consisting of nitrites, sulfites, bisulfites, pyrosulfites, thiosulfates, sulfur dioxide, nitrogen oxide, oxalic acid, formaldehyde, hydrazine, hydrogen peroxide and hydroxylamine.
Sources & evidence
- ORD record
- ord-9e8fa05545214bad9b42db086918fb27
- Source dataset
- uspto-grants-1981_02
- Patent number
- US04252717
Reaction notes
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