Chlorotrimethylsilane → HCID 54206259, compound

HRID 1413984Notes

Reaction equation

HRID 1413984 reaction equation
C[O:2][C:3]1([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)O[CH:8]2[CH:5]([CH2:6][CH2:7]2)[O:4]1.C[Si](C)(C)[Cl:18]>C(Cl)Cl>[Cl:18][C@@H:8]1[CH2:7][CH2:6][C@H:5]1[O:4][C:3](=[O:2])[C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

4

Reactant 2

HCID 6397ChlorotrimethylsilaneHCID 12791331HCID 12791331, compound

Product 1

HCID 54206259HCID 54206259, compoundYield 98%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

26.0 g (0.126 mol) of 3-methoxy-3-phenyl-2,4-dioxa-bicyclo[3,2,0]heptane (stereoisomer mixture) and 17.1 g (0.16 mol) of trimethylchlorosilane in 70 ml of methylene chloride are heated to the reflux for 14 hours. Evaporation and fractional distillation in vacuo gives 25.9 g (98%) of trans-1-chloro-2-benzoyloxy-cyclobutane. Boiling point0.35 94°-95°, melting point 20°.

Workup

  1. temperaturereflux for 14 hours
  2. customEvaporation and fractional distillation in vacuo

Sources & evidence

ORD record
ord-e4e1e310373b4ce4b8265815dd8d3468
Source dataset
uspto-grants-1981_02
Patent number
US04252738

Reaction notes

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