creatinine → HCID 131712086, compound

HRID 1414030Notes

Reaction equation

HRID 1414030 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[C:12]2[C:7](=[CH:8][CH:9]=[C:10]([C:13]([N:15]3[CH2:20][CH2:19][O:18][CH2:17][CH2:16]3)=[O:14])[CH:11]=2)[NH:6][CH:5]=1.CN1C(N)=N[C:24](=[O:25])[CH2:23]1.S(=O)(=O)(O)O.O.[CH2:35]([OH:37])C>>[N:15]1([C:13]([C:10]2[CH:11]=[C:12]3[C:7](=[CH:8][CH:9]=2)[NH:6][CH:5]=[C:4]3[CH2:3][CH2:2][NH:1][C:35](=[O:37])[O:25][CH2:24][C:23]2[CH:11]=[CH:12][CH:4]=[CH:3][CH:2]=2)=[O:14])[CH2:20][CH2:19][O:18][CH2:17][CH2:16]1

Participants

6

Reactant 5

HCID 588creatinineHCID 702EthanolHCID 962WaterHCID 1118Sulfuric AcidHCID 20289498HCID 20289498, compound

Product 1

HCID 131712086HCID 131712086, compound

Procedure

(ii)c [2-[5-[(4-Morpholinyl)carbonyl]-1H-indol-3-yl]ethyl]carbamic acid, phenylmethyl ester (1.5 g) gave 4-[[3-(2-aminoethyl)-1H-indol-5-yl]carbonyl] morpholine, compound with creatinine, sulphuric acid and water (1:1:1:1) (0.65 g) as a white crystalline solid m.p. 178°-181° C. (from aqueous ethanol)

Sources & evidence

ORD record
ord-a7c2e112d4ca4b8a8bbd8d9164b961fd
Source dataset
uspto-grants-1981_02
Patent number
US04252803

Reaction notes

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