HCID 86737513, compound → HCID 86737512, compound

Participants

Reaction Steps

A solution of 3-[2-[(methyl(phenylmethyl)amino]ethyl]-1H-indole-5-carboxamide (1.05 g) in absolute ethanol (200 ml) was hydrogenated over pre-reduced palladium oxide on charcoal (10%, 0.5 g) for 2.5 hours at room temperature and pressure. The catalyst was filtered off and the filtrate evaporated in vacuo to give the title compound (0.7 g) as a colourless crystalline solid. T.L.C. Silica, ethanol:water (1:1) Rf 0.3

Provenance & Evidence