Potassium Hydroxide → HCID 70393882, compound

Participants

Reaction Steps

250 g of potassium hydroxide were added to a solution of 500 g of trans (3-methoxy-2-piperidyl)-2-propanone hydrobromide in 500 ml of ice water and the mixture was extracted with methylene chloride. The combined organic phases were dried, treated with 25 g of carbon black and evaporated to dryness under reduced pressure to obtain 338.5 g of trans (3-methoxy-2-piperidyl)-2-propanone in the form of an oil which was used as is for the next step.

Provenance & Evidence