Hydrogen Bromide → HCID 86737516, compound

Participants

Reaction Steps

Using the procedure of U.S. Pat. No. 2,775,597, the product of Step A4 was reacted with a solution of 15% hydrogen bromide in acetic acid for 2 hours at room temperature and the mixture was evaporated to dryness under reduced pressure to obtain dextrorotary trans 3-bromo-1-(3-methoxy-2-piperidyl)-2-propanone hydrobromide melting at 143° C. and having a specific rotation [α]D20 =+25° (c=1% in methanol).

Provenance & Evidence