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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1414348Generated: November 1, 2026

Diisobutylaluminumhydride → 8-Methyl-8-azabicyclo(3.2.1)octan-3-ol

https://huagongshe.com/reaction/1414348

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisobutylaluminumhydrideHCID 21225700—
ReactantHCID 21487037HCID 21487037—
SolventBenzeneHCID 241—
Product8-Methyl-8-azabicyclo(3.2.1)octan-3-olHCID 8424—

Reaction Steps

A process as claimed in claim 8, wherein N-carbomethoxy-8-azabicyclo (3,2,1) octan-3-one is reacted with diisobutyl-aluminumhydride in benzene and at room temperature, to produce tropine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS04001249
Source datasetuspto-grants-1977_01
ORD IDord-e1d313f46bdc468b8ee12843374c4a66
Source noteuspto-grants-1977_01