Boron trifluoride etherate → Boron trifluoride etherate
Reaction equation
[B:1]([F:4])([F:3])[F:2].[CH3:5][CH2:6][O:7][CH2:8][CH3:9]>CO>[B:1]([F:4])([F:3])[F:2].[CH3:5][CH2:6][O:7][CH2:8][CH3:9].[CH3:6][O:7][CH3:8]Participants
4
Reactant 1
Product 2
Reagents, catalysts & solvents 1
Procedure
Another method for the alkylation of the 3-hydroxy is by reaction with an alcohol in the presence of boron trifluoride etherate. Thus, methanol and boron trifluoride etherate yield a methyl ether at a reaction temperature of about 25° C. followed conveniently by thin layer chromatography.
Sources & evidence
- ORD record
- ord-34ecc80fd69f4fb3b1962b1e33176e4d
- Source dataset
- uspto-grants-1977_01
- Patent number
- US04001300
Reaction notes
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