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HRID1414445

反应详情

EQUATION

反应方程式

HRID 1414445 的结构方程式

REACTANTS

反应物

2
结构：Cc1ccc(S(=O)(=O)Cl)cc1
HCID7397

p-Toluenesulfonyl chloride

C7H7ClO2S

结构：Cc1ccc(S(=O)(=O)N(CCO)CCO)cc1
HCID81565

N,N-Bis(2-hydroxyethyl)-p-toluenesulphonamide

C11H17NO4S

PRODUCTS

生成物

1
结构：Cc1ccc(S(=O)(=O)OCCN(CCOS(=O)(=O)c2ccc(C)cc2)S(=O)(=O)c2ccc(C)cc2)cc1
HCID267409

[(4-Methylbenzene-1-sulfonyl)azanediyl]di(ethane-2,1-diyl) bis(4-methylbenzene-1-sulfonate)

C25H29NO8S3

AUXILIARIES

试剂、催化剂与溶剂

1
结构：c1ccncc1
溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

Procedure 3 is illustrated with the preparation of (-)-(RR)-8a' and (+)-(RR)-8b', with (-)-(R)-6f' as a byproduct. In dry pyridine at 0°, N,N-bis-(2-hydroxyethyl)-p-toluenesulfonamide (m.p. 96°-99°) was tosylated with tosyl chloride by the standard method to give N,O,O'-tritosyldiethanolamine, m.p. 85°-87°. [Can. J. Chem. 45, 1555 (1967) gives 78°-79°].

WORKUP

后处理

  1. customProcedure 3 is illustrated with the preparation of (-)-(RR)-8a' and (+)-(RR)-8b', with (-)-(R)-6f' as a byproduct
  2. customat 0°