Oxalic Acid → HCID 21411023, compound

HRID 1414457Notes

Reaction equation

HRID 1414457 reaction equation
[CH2:1]([N:4]([CH2:8][CH:9]([OH:24])[CH2:10][CH:11]([C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1)[CH2:5][CH2:6][CH3:7])[CH2:2][CH3:3].[C:25]([OH:30])(=[O:29])[C:26]([OH:28])=[O:27]>C(OCC)(=O)C>[C:25]([O-:30])(=[O:29])[C:26]([O-:28])=[O:27].[CH2:1]([NH+:4]([CH2:8][CH:9]([OH:24])[CH2:10][CH:11]([C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH2:5][CH2:6][CH3:7])[CH2:2][CH3:3].[CH2:1]([NH+:4]([CH2:8][CH:9]([OH:24])[CH2:10][CH:11]([C:12]1[CH:13]=[CH:14][CH:15]=[CH:16][CH:17]=1)[C:18]1[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=1)[CH2:5][CH2:6][CH3:7])[CH2:2][CH3:3]

Participants

4

Reactant 2

HCID 971Oxalic AcidHCID 21411024HCID 21411024, compound

Product 1

HCID 21411023HCID 21411023, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

The N,N-di-n-propyl-4,4-diphenyl-2-hydroxybutylamine from Example 1 above was dissolved in 50 ml. of ethyl acetate and oxalic acid was added to the solution. The precipitated product was collected by filtration and was recrystallized from ethyl alcohol. Colorless crystalline N,N-di-n-propyl-4,4-diphenyl-2-hydroxybutylaminium oxalate was collected by filtration and dried. M.P. 121°-122° C.

Workup

  1. filtrationThe precipitated product was collected by filtration
  2. customwas recrystallized from ethyl alcohol
  3. filtrationColorless crystalline N,N-di-n-propyl-4,4-diphenyl-2-hydroxybutylaminium oxalate was collected by filtration
  4. customdried

Sources & evidence

ORD record
ord-86c288a4c6ac4797b12959debcf84902
Source dataset
uspto-grants-1977_01
Patent number
US04001328

Reaction notes

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