Hydrochloric Acid → HCID 21487808, compound

HRID 1414527Notes

Reaction equation

HRID 1414527 reaction equation
[Cl:1][CH2:2][CH2:3][C:4]1([CH2:18][CH2:19][Cl:20])[C:17]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[S:11][C:10]2[C:5]1=[CH:6][CH:7]=[CH:8][CH:9]=2.[Cl-].[Cl-].IC1C=CC=CC=1.Cl.[OH2:31]>N1C=CC=CC=1>[Cl:20][CH2:19][CH2:18][C:4]1([CH2:3][CH2:2][Cl:1])[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:10]=2[S:11](=[O:31])[C:12]2[C:17]1=[CH:16][CH:15]=[CH:14][CH:13]=2

Participants

6

Reactant 4

HCID 313Hydrochloric AcidHCID 962Water2×HCID 13166207CID 13166207HCID 21487798HCID 21487798, compound

Product 1

HCID 21487808HCID 21487808, compound

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent2×

Procedure

A solution of 9,9-bis(2'-chloroethyl)thioxanthene in pyridine (25 ml.) and water (5 ml.) is cooled in an ice/salt bath to -5° to 0° C. and a solution of iodobenzene dichloride (2.7 g.) in dry pyridine (10 ml.) is added slowly during 15 minutes with stirring. Stirring at 0° C. is continued for a further 15 minutes, the reaction mixture is poured into water, acidified with concentrated hydrochloric acid and extracted with chloroform. The product is crystallised from cyclohexane to give 9,9-bis(2'-chloroethyl)-thioxanthene 10-oxide, m.p. 126°-127° C.

Workup

  1. stirringStirring at 0° C.
  2. extractionextracted with chloroform
  3. customThe product is crystallised from cyclohexane

Sources & evidence

ORD record
ord-702427de5eb743f2990a1577545a29b9
Source dataset
uspto-grants-1977_01
Patent number
US04001418

Reaction notes

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