Aluminum isopropoxide → HCID 21487823, compound

HRID 1414533Notes

Reaction equation

HRID 1414533 reaction equation
[Cl:1][C:2]1[CH:15]=[CH:14][C:13]2[S:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][C:10]=3[O:16][CH3:17])[C:5](=O)[C:4]=2[CH:3]=1.CC(C)[O-].[Al+3].CC(C)[O-].CC(C)[O-]>Cl>[Cl:1][C:2]1[CH:15]=[CH:14][C:13]2[S:12][C:11]3[C:6](=[CH:7][CH:8]=[CH:9][C:10]=3[O:16][CH3:17])[CH2:5][C:4]=2[CH:3]=1

Participants

4

Reactant 2

HCID 11143Aluminum isopropoxideHCID 21487791HCID 21487791, compound

Product 1

HCID 21487823HCID 21487823, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Conditions

Temperature
190 °C

Procedure

An intimate mixture of 2-chloro-5-methoxythioxanth-9-one (8 g.) and aluminium isopropoxide (32 g.) is heated and stirred in an atmosphere of nitrogen for 31/2 hours at 190° C. The mixture is cooled, 2N-hydrochloric acid (210 ml.) is added and the mixture extracted three times with ether. The combined ether extracts are washed with brine, dried over MgSO4 and the solvent evaporated in vacuo to give 2-chloro-5-methoxythioxanthene, m.p. 95°-96° C. on recrystallisation from methanol.

Workup

  1. temperatureis heated
  2. temperatureThe mixture is cooled
  3. extractionthe mixture extracted three times with ether
  4. washThe combined ether extracts are washed with brine
  5. dry with materialdried over MgSO4
  6. customthe solvent evaporated in vacuo

Sources & evidence

ORD record
ord-8bfef4e0d8de4eeca5c1dd3855a43294
Source dataset
uspto-grants-1977_01
Patent number
US04001418

Reaction notes

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