Acetone → HCID 21487973, compound

HRID 1414625Notes

Reaction equation

[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[O:9][C:10]3[CH:24]=[CH:23][CH:22]=[CH:21][C:11]=3[C:12]=2C2C=C(C)C=C(C)C=2)=[CH:4][CH:3]=1.[C:25](=[O:28])([O-])[O-].[K+].[K+].[CH3:31][N:32]([CH3:37])[CH2:33][CH2:34][CH2:35]Cl.[CH3:38][C:39]([CH3:41])=O>>[CH3:31][N:32]([CH3:37])[CH2:33][CH2:34][CH2:35][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[O:9][C:10]3[CH:24]=[CH:23][CH:22]=[CH:21][C:11]=3[C:12]=2[C:25](=[O:28])[C:39]2[CH:41]=[C:7]([CH3:6])[CH:2]=[C:3]([CH3:4])[CH:38]=2)=[CH:6][CH:7]=1

Participants

Reactant 4

HCID 180Acetone

HCID 11430Potassium Carbonate

HCID 669603-Chloro-N,N-dimethyl-1-propanamine

HCID 21487902HCID 21487902, compound

Product 1

HCID 21487973HCID 21487973, compound

Procedure

Treatment of 2-p-hydroxyphenyl-3-(3',5'-dimethylphenyl)benzofuran with potassium carbonate and 3-dimethylaminopropyl chloride in dry acetone by the procedure described in Example 31 gave the title compound.

Sources & evidence

ORD record: ord-5994e338e9d54d69b413a13d76c1352d
Source dataset: uspto-grants-1977_01
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04001426

Reaction notes

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