反应详情

A mixture of 2-methylthio-4H-3,1-benzothiazine (39 g, 0.20 mole) and 3,4-dichloroaniline (32.4 g, 0.20 mole) in n-butanol (150 ml) was refluxed overnight. After cooling in ice, the solid was collected by filtration and recrystallized from ethanol to give 27 g (43.8%) of product. Recrystallization from ethanol gave analytical sample m.p. 207°-208°.

1. temperaturewas refluxed overnight
2. temperatureAfter cooling in ice
3. filtrationthe solid was collected by filtration
4. customrecrystallized from ethanol