HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dichloroaniline → N-(3,4-Dichlorophenyl)-4H-3,1-benzothiazin-2-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dichloroaniline | HCID 7257 | — |
| Reactant | 2-(Methylsulfanyl)-4H-3,1-benzothiazine | HCID 21484890 | — |
| Solvent | 1-Butanol | HCID 263 | — |
| Product | N-(3,4-Dichlorophenyl)-4H-3,1-benzothiazin-2-amine | HCID 21484883 | 43.8% |
Reaction Steps
A mixture of 2-methylthio-4H-3,1-benzothiazine (39 g, 0.20 mole) and 3,4-dichloroaniline (32.4 g, 0.20 mole) in n-butanol (150 ml) was refluxed overnight. After cooling in ice, the solid was collected by filtration and recrystallized from ethanol to give 27 g (43.8%) of product. Recrystallization from ethanol gave analytical sample m.p. 207°-208°.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04002620 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-e120507017f14f668aaf8ce8552ac46b |
| Source note | uspto-grants-1977_01 |