HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → 3-Acetyl-1-methylpyrrole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | 2-Acetyl-1-methylpyrrole | HCID 61240 | — |
| Product | 3-Acetyl-1-methylpyrrole | HCID 523057 | — |
Reaction Steps
A solution of 3.0g of 2-acetyl-1-methylpyrrole in 30 ml of trifluoroacetic acid is heated under reflux for 90 minutes. The solvent is then evaporated in vacuo and the residue is partitioned between chloroform and sodium bicarbonate solution. The chloroform layer is dried and the solvent evaporated in vacuo to give 3-acetyl-1-methylpyrrole as a brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04002643 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-51ba8b3305814f219d753510c037a1d5 |
| Source note | uspto-grants-1977_01 |