反应详情

Ethyl 3-hydroxy-3-phenylpropanoate (19 g, 0.1 mole) was refluxed in a solution of KOH (10 g, 0.2 mole) in ethanol for two hours. The solvent was removed in vacuo and the residue was dissolved in H2O. The H2O solution was extracted with ethyl ether, then acidified with 37% hydrochloric acid. The oily product was extracted out with chloroform and the chloroform was removed in vacuo to yield 10 g (62.5%).

1. customThe solvent was removed in vacuo
2. dissolutionthe residue was dissolved in H2O
3. extractionThe H2O solution was extracted with ethyl ether
4. extractionThe oily product was extracted out with chloroform
5. customthe chloroform was removed in vacuo
6. customto yield 10 g (62.5%)