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Potassium Hydroxide → 3-Hydroxy-3-phenylpropanoic acid
関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|---|---|---|
| 反応物 | Potassium Hydroxide | HCID 14797 | — |
| 反応物 | Ethyl 3-phenylhydracrylate, (+-)- | HCID 99818 | — |
| 溶媒 | Ethanol | HCID 702 | — |
| 生成物 | 3-Hydroxy-3-phenylpropanoic acid | HCID 92959 | — |
反応手順
Ethyl 3-hydroxy-3-phenylpropanoate (19 g, 0.1 mole) was refluxed in a solution of KOH (10 g, 0.2 mole) in ethanol for two hours. The solvent was removed in vacuo and the residue was dissolved in H2O. The H2O solution was extracted with ethyl ether, then acidified with 37% hydrochloric acid. The oily product was extracted out with chloroform and the chloroform was removed in vacuo to yield 10 g (62.5%).
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 特許番号 | US04002660 |
| 出典データセット | uspto-grants-1977_01 |
| ORD ID | ord-cdcbffa4f09742e9845325766a34354c |
| 出典メモ | uspto-grants-1977_01 |