HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Carbonate → N-{4-[(Methylsulfanyl)methoxy]-2-nitrophenyl}acetamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Chloromethyl methyl sulfide | HCID 16916 | — |
| Reactant | N-(4-hydroxy-2-nitrophenyl)acetamide | HCID 4024832 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | N-{4-[(Methylsulfanyl)methoxy]-2-nitrophenyl}acetamide | HCID 20362815 | — |
Reaction Steps
6 G. of 1-acetamido-4-hydroxy-2-nitrobenzene is added to 200 ml. acetone containing 25 g. potassium carbonate and 6 ml. chloromethyl methyl sulfide. The mixture is heated at reflux for four hours and is filtered. The acetone is evaporated leaving 1-acetamido-4-methylthiomethoxy-2-nitrobenzene as a gum. This is purified by column chromatography.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04002640 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-1486d475a7c74fb59e597df7bb36bcd7 |
| Source note | uspto-grants-1977_01 |