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HRID1414779

反应详情

EQUATION

反应方程式

HRID 1414779 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[K+].[K+]
HCID11430

Potassium Carbonate

CK2O3

结构：CSCCl
HCID16916

Chlorodimethyl sulfide

C2H5ClS

结构：CC(=O)Nc1ccc(O)cc1[N+](=O)[O-]
HCID4024832

N-(4-hydroxy-2-nitrophenyl)acetamide

C8H8N2O4

PRODUCTS

生成物

1
结构：CSCOc1ccc(NC(C)=O)c([N+](=O)[O-])c1
HCID20362815

N-{4-[(Methylsulfanyl)methoxy]-2-nitrophenyl}acetamide

C10H12N2O4S

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC(C)=O
溶剂HCID180

Acetone

C3H6O

PROCEDURE

实验过程

6 G. of 1-acetamido-4-hydroxy-2-nitrobenzene is added to 200 ml. acetone containing 25 g. potassium carbonate and 6 ml. chloromethyl methyl sulfide. The mixture is heated at reflux for four hours and is filtered. The acetone is evaporated leaving 1-acetamido-4-methylthiomethoxy-2-nitrobenzene as a gum. This is purified by column chromatography.

WORKUP

后处理

  1. temperatureThe mixture is heated
  2. temperatureat reflux for four hours
  3. filtrationis filtered
  4. customThe acetone is evaporated