反应详情

1.4 G. of 1 -acetamido-2-nitro-4-methoxymethylthiobenzene is treated in 6 ml. of methanol with 3 ml. of 5N aqueous sodium hydroxide solution and refluxed for 15 minutes. The solvent is removed under vacuum and the residue diluted with water and extracted with chloroform. Evaporation of the chloroform yields 2-nitro-4-methoxymethylthioaniline as reddish crystals.

1. customThe solvent is removed under vacuum
2. additionthe residue diluted with water
3. extractionextracted with chloroform
4. customEvaporation of the chloroform