7-Methoxy-3,7-Dimethyloctanal → 1-Octanol, 7-methoxy-3,7-dimethyl-

93.2 g. of 7-methoxycitronellal dissolved in 200 ml. of absolute diethyl ether are added dropwise with ice cooling to a suspension of 7.6 g. of lithium aluminum hydride in 500 ml. of absolute diethyl ether. Subsequently, the mixture is stirred for 30 minutes and decomposed in the cold by the addition of 100 ml. of aqueous ammonium chloride solution. The resulting mass is filtered through diatomaceous earth, the filtrate washed once with saturated aqueous ammonium chloride solution and once with saturated aqueous sodium chloride solution, dried over sodium sulfate and evaporated. The residue is distilled at 0.1 mmHg. There is obtained pure 3,7-dimethyl-7-methoxy-1-octanol of boiling point 87° C./0.1 mmHg; nD20 = 1.4456.

1. additiondecomposed in the cold by the addition of 100 ml
2. filtrationThe resulting mass is filtered through diatomaceous earth
3. washthe filtrate washed once with saturated aqueous ammonium chloride solution and once with saturated aqueous sodium chloride solution
4. dry with materialdried over sodium sulfate
5. customevaporated
6. distillationThe residue is distilled at 0.1 mmHg

ORD-Eintrag

ord-a77c08cb12cc4c3ea5c1504bb4eb23e0

Quelldatensatz

uspto-grants-1977_01

DOI

10.6084/m9.figshare.5104873.v1

Patentnummer

US04002647