1,1-Bis(methylthio)-2-nitroethylene → 1-Nitro-2-methylthio-2-[4-(2-pyridyl)butylamino]ethylene

HRID 1414884Notes

Reaction equation

HRID 1414884 reaction equation
[NH2:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][N:7]=1.[N+:12]([CH:15]=[C:16](SC)[S:17][CH3:18])([O-:14])=[O:13]>N1C=CC=CC=1>[N+:12]([CH:15]=[C:16]([S:17][CH3:18])[NH:1][CH2:2][CH2:3][CH2:4][CH2:5][C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][N:7]=1)([O-:14])=[O:13]

Participants

4

Reactant 2

HCID 836231,1-Bis(methylthio)-2-nitroethyleneHCID 135110834-(Pyridin-2-yl)butan-1-amine

Product 1

HCID 706192371-Nitro-2-methylthio-2-[4-(2-pyridyl)butylamino]ethylene

Reagents, catalysts & solvents 1

HCID 1049PyridineSolvent

Procedure

2-(4-Aminobutyl)pyridine was reacted with 1-nitro-2,2-bis-methylthio-ethylene in pyridine at 60° for 3.5 hours. Concentration of the reaction mixture and crystallisation yielded 1-nitro-2-methylthio-2-[4-(2-pyridyl)butylamino]ethylene, m.p. 78°.

Workup

  1. customConcentration of the reaction mixture and crystallisation

Sources & evidence

ORD record
ord-ddcfdb851440463b886b2378596f3841
Source dataset
uspto-grants-1977_01
Patent number
US04002759

Reaction notes

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