Methane → HCID 54153729, compound

HRID 1414983Notes

Reaction equation

HRID 1414983 reaction equation
[CH2:1]([C@:3]12[CH2:11][CH2:10][C:9]3[C:12]4[CH:13]=[CH:14][C:15]([OH:20])=[CH:16][C:17]=4[CH2:18][CH2:19][C:8]=3[C:7]1=[CH:6][CH2:5][C@@H:4]2[OH:21])[CH3:2].C.[H][H]>C1C=CC=CC=1>[CH2:1]([C@:3]12[CH2:11][CH2:10][C:9]3[C:12]4[CH:13]=[CH:14][C:15]([OH:20])=[CH:16][C:17]=4[CH2:18][CH2:19][C:8]=3[C@@H:7]1[CH2:6][CH2:5][C@@H:4]2[OH:21])[CH3:2]

Participants

5

Reactant 3

HCID 297MethaneHCID 22790403HCID 22790403, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 54153729HCID 54153729, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Shake 13β-ethylgona-1,3,5-(10),8,14-pentaene-3,17β-diol (0.28 g.) in benzene (35 cc.) with 10% palladised charcoal (300 mg.) in an atmosphere of hydrogen until 25 cc. of hydrogen has been absorbed. Filter off the catalyst, evaporate the solvent and recrystallize the residue from methanol to obtain the title product, m.p. 234°-8°; ultraviolet absorption peak at 280 mμ (ε 41,200).

Workup

  1. customof hydrogen has been absorbed
  2. filtrationFilter off the catalyst
  3. customevaporate the solvent
  4. customrecrystallize the residue from methanol

Sources & evidence

ORD record
ord-40d4b0c4267e482e9e520c818b1db43c
Source dataset
uspto-grants-1977_01
Patent number
US04002746

Reaction notes

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