1-Nitro-4-(3-phenylpropoxy)benzene → Aniline, p-(3-phenylpropoxy)-

HRID 1415348Notes

Reaction equation

HRID 1415348 reaction equation
[C:1]1([CH2:7][CH2:8][CH2:9][O:10][C:11]2[CH:16]=[CH:15][C:14]([N+:17]([O-])=O)=[CH:13][CH:12]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>CO.[Ni].[H][H]>[C:1]1([CH2:7][CH2:8][CH2:9][O:10][C:11]2[CH:12]=[CH:13][C:14]([NH2:17])=[CH:15][CH:16]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

5

Reactant 1

HCID 214818451-Nitro-4-(3-phenylpropoxy)benzene

Product 1

HCID 42154Aniline, p-(3-phenylpropoxy)-

Reagents, catalysts & solvents 3

HCID 935NickelCatalystHCID 887MethanolSolventHCID 178418361HCID 178418361, compoundSolvent

Procedure

99 g of 4-(3'-phenyl-propoxy)-nitrobenzene is dissolved in 2000 ml of methanol and hydrogenated with Raney nickel until the absorption of hydrogen is completed. The catalyst is filtered off and the filtrate is concentrated by evaporation to obtain, as a crystalline residue, 4-(3'-phenylpropoxy)-aniline having a melting point of 55°- 57°. -

Workup

  1. filtrationThe catalyst is filtered off
  2. concentrationthe filtrate is concentrated by evaporation

Sources & evidence

ORD record
ord-b76eb5365a4e442faeb86e2e4339cc8a
Source dataset
uspto-grants-1977_01
Patent number
US04004907

Reaction notes

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