HCID 15739784, compound → HCID 15717143, compound

HRID 1415350Notes

Reaction equation

HRID 1415350 reaction equation
[C:1]1([CH2:7][CH2:8][S:9][C:10]2[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][CH:11]=2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1>CO.[Ni]>[C:1]1([CH2:7][CH2:8][S:9][C:10]2[CH:11]=[CH:12][C:13]([NH2:16])=[CH:14][CH:15]=2)[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

Participants

4

Reactant 1

HCID 15739784HCID 15739784, compound

Product 1

HCID 15717143HCID 15717143, compound

Reagents, catalysts & solvents 2

HCID 935NickelCatalystHCID 887MethanolSolvent

Procedure

86 g of 4-(2'-phenyl-ethylthio)-nitrobenzene is dissolved in 900 ml of methanol and catalytically hydrogenated with Raney nickel. After completion of the absorption of hydrogen, the catalyst is filtered off and the filtrate is concentrated by evaporation. There is obtained 4-(2'-phenyl-ethylthio)-aniline as oily residue, which is used without purification in the next reaction stage.

Workup

  1. customAfter completion of the absorption of hydrogen
  2. filtrationthe catalyst is filtered off
  3. concentrationthe filtrate is concentrated by evaporation

Sources & evidence

ORD record
ord-d10bfe646bd847acad87b0650e9d2499
Source dataset
uspto-grants-1977_01
Patent number
US04004907

Reaction notes

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