Methanol → HCID 57324323, compound

HRID 1415421Notes

Reaction equation

HRID 1415421 reaction equation
[CH:1]1([C:4](=O)[CH:5]=[CH:6][C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([Cl:13])[CH:8]=2)[CH2:3][CH2:2]1.[N+:15]([CH2:18][CH3:19])([O-:17])=[O:16].[Na].C[OH:22]>>[CH:1]1([CH2:4][C:5](=[O:22])[CH:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([Cl:13])[CH:8]=2)[CH:18]([N+:15]([O-:17])=[O:16])[CH3:19])[CH2:3][CH2:2]1

Participants

5

Reactant 4

HCID 887MethanolHCID 6587NitroethaneHCID 5360545SodiumHCID 53869264HCID 53869264, compound

Product 1

HCID 57324323HCID 57324323, compound

Procedure

The procedure of Example IX using 33 g of 1-cyclopropyl-3-(m-chlorophenyl)prop-2-en-1-one, 15 ml of nitroethane and 2 g of sodium in 150 ml of methanol, gives 33.5 g of 1-cyclopropyl-3-(m-chlorophenyl)-4-nitropentanone as an oily residue which is used in the crude state for the remainder of the operations.

Sources & evidence

ORD record
ord-10ec116cc4274cdf93b9ca61480681f3
Source dataset
uspto-grants-1977_01
Patent number
US04005103

Reaction notes

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