Hydrochloric Acid → 4-[(Pyridin-2-yl)sulfanyl]benzene-1,2-diamine

HRID 1415522Notes

Reaction equation

HRID 1415522 reaction equation
[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)=[CH:4][C:3]=1[N+:15]([O-])=O.Cl.C(=O)(O)[O-].[K+]>>[NH2:1][C:2]1[CH:7]=[CH:6][C:5]([S:8][C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][N:10]=2)=[CH:4][C:3]=1[NH2:15]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 516893Potassium BicarbonateHCID 214827702-Nitro-4-[(pyridin-2-yl)sulfanyl]aniline

Product 1

HCID 214827934-[(Pyridin-2-yl)sulfanyl]benzene-1,2-diamine

Procedure

2.3 G. of 1-amino-2-nitro-4-(pyrid-2-ylthio)benzene in 12 ml. concentrated hydrochloric acid is treated with 12 g. of stannous chloride on the steam bath for 15 minutes. The cooled solution is treated with an excess of potassium bicarbonate and extracted with chloroform and filtered. The chloroform layer is separated, dried and evaporated to yield 1,2-diamino-4-(pyrid-2-ylthio)benzene.

Workup

  1. extractionextracted with chloroform
  2. filtrationfiltered
  3. customThe chloroform layer is separated
  4. customdried
  5. customevaporated

Sources & evidence

ORD record
ord-dd00b1b9cff24606a0060af261eaa36d
Source dataset
uspto-grants-1977_01
Patent number
US04005202

Reaction notes

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