huagongshe.com
HRID1415535

反应详情

EQUATION

反应方程式

HRID 1415535 的结构方程式

REACTANTS

反应物

2
结构：CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
HCID8567

(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentol

C7H17NO5

结构：CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O.O.O.O
HCID62883

Amoxicillin hydrate (1:3)

C16H25N3O8S

PRODUCTS

生成物

2
结构：CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO
HCID8567

(2R,3R,4R,5S)-6-(Methylamino)hexane-1,2,3,4,5-pentol

C7H17NO5

结构：CC1(C)S[C@@H]2[C@H](NC(=O)[C@H](N)c3ccc(O)cc3)C(=O)N2[C@H]1C(=O)O
HCID33613

Amoxicillin

C16H19N3O5S

AUXILIARIES

试剂、催化剂与溶剂

1
结构：O
溶剂HCID962

Water

H2O

PROCEDURE

实验过程

3 G. of N-methyl-D-glucamine are added to a suspension of 6 g. of amoxicillin trihydrate in 80 ml. of water and stirred at 5° C. Insoluble material is fitered off under suction and the resulting filtrate is lyophilized. There is thus obtained the N-methyl-D-glucamine salt of amoxicillin. Melting point: about 160° C. (decomposition). [α]D25 = + 133° (c =1 in water).