N-Methyl-D-glucamine → N-Methyl-D-glucamine

Participants

Reaction Steps

3 G. of N-methyl-D-glucamine are added to a suspension of 6 g. of amoxicillin trihydrate in 80 ml. of water and stirred at 5° C. Insoluble material is fitered off under suction and the resulting filtrate is lyophilized. There is thus obtained the N-methyl-D-glucamine salt of amoxicillin. Melting point: about 160° C. (decomposition). [α]D25 = + 133° (c =1 in water).

Provenance & Evidence