Potassium Carbonate → HCID 21482950, compound

Participants

Reaction Steps

The hydrochloride is dissolved in water (12 cc.) and anhydrous potassium carbonate (3.9 g.) is added. The mixture is extracted with ethyl acetate (40 cc.) and the extracts are dried over anhydrous potassium carbonate. After filtration, the solvent is evaporated under reduced pressure (300 mm.Hg) and an oil (4 g.) is obtained which crystallises after treatment with cyclohexane (700 cc.). 2-(2-Pyridyl)-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole (3.1 g.), melting at 70° C., is thus obtained.

Provenance & Evidence