3,3-Diethoxy-1-(phenylmethyl)piperidine → HCID 21482822, compound

HRID 1415562Notes

Reaction equation

HRID 1415562 reaction equation
C([N:8]1[CH2:13][CH2:12][CH2:11][C:10]([O:17][CH2:18][CH3:19])([O:14][CH2:15][CH3:16])[CH2:9]1)C1C=CC=CC=1.[H][H]>[Pd]>[CH2:18]([O:17][C:10]1([O:14][CH2:15][CH3:16])[CH2:11][CH2:12][CH2:13][NH:8][CH2:9]1)[CH3:19]

Participants

4

Reactant 2

HCID 214828783,3-Diethoxy-1-(phenylmethyl)piperidineHCID 178418361HCID 178418361, compound

Product 1

HCID 21482822HCID 21482822, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

A mixture of 15 g. of 1-benzyl-3,3-diethoxypiperidine in 100 ml. of absolute alcohol and 0.5 g. of 10% palladium on charcoal is shaken over 50 p.s.i. of hydrogen at 50° C. for six hours. The catalyst is filtered and washed with ethanol. The solvent is removed by distillation to give 3,3-diethoxypiperidine.

Workup

  1. additionA mixture of 15 g
  2. filtrationThe catalyst is filtered
  3. washwashed with ethanol
  4. customThe solvent is removed by distillation

Sources & evidence

ORD record
ord-c68437865866452186479d43a9b44b81
Source dataset
uspto-grants-1977_01
Patent number
US04005208

Reaction notes

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