HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylcarbamoyl Chloride → 1-Piperidinecarboxamide, 3-amino-N,N-dimethyl-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylcarbamoyl Chloride | HCID 6598 | — |
| Reactant | Hydrazine hydrate (1:1) | HCID 24654 | — |
| Reactant | 2-(Piperidin-3-yl)-1H-isoindole-1,3(2H)-dione | HCID 19972263 | — |
| Reactant | 1-(N,N-dimethylcarbamoyl)-3-phthalimidopiperidine | HCID 21482854 | — |
| Product | 1-Piperidinecarboxamide, 3-amino-N,N-dimethyl- | HCID 21482877 | — |
Reaction Steps
In addition, reacting 3-phthalimidopiperidine with N,N-dimethylcarbamoyl chloride and treating the resulting 1-(N,N-dimethylcarbamoyl)-3-phthalimidopiperidine with hydrazine hydrate gives 1-(N,N-dimethylcarbamoyl)-3-aminopiperidine. Reacting this piperidine compound with 9-acetoxyxanthene by the procedure of Example 1 gives N-[1-(N,N-dimethylcarbamoyl)-3-piperidinyl]-9-xanthenylamine.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04005208 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-1d273901cc1440d693e28e2ab4c0e80c |
| Source note | uspto-grants-1977_01 |