Hydrazine hydrate (1:1) → HCID 21482310, compound

HRID 1415608Notes

Reaction equation

HRID 1415608 reaction equation
[Cl:1][C:2]1[CH:37]=[CH:36][CH:35]=[CH:34][C:3]=1[C:4]([C:6]1[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=1[N:12]1[C:16]([CH2:17][N:18]2C(=O)C3=CC=CC=C3C2=O)=[C:15]([CH3:29])[N:14]=[C:13]1[CH2:30][N:31]([CH3:33])[CH3:32])=O.O.NN>C(O)C>[Cl:1][C:2]1[CH:37]=[CH:36][CH:35]=[CH:34][C:3]=1[C:4]1[C:6]2[CH:11]=[CH:10][CH:9]=[CH:8][C:7]=2[N:12]2[C:13]([CH2:30][N:31]([CH3:32])[CH3:33])=[N:14][C:15]([CH3:29])=[C:16]2[CH2:17][N:18]=1

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 21482340HCID 21482340, compound

Product 1

HCID 21482310HCID 21482310, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

In the manner given in Example 4, N-[[1-[2-(o-chlorobenzoyl)phenyl]-2-[(dimethylamino)methyl]-4-methylimidazol-5-yl]methyl]phthalimide in ethanol is heated with hydrazine hydrate to give 6-(o-chlorophenyl)-1-[(dimethylamino)-methyl]-3-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine.

Sources & evidence

ORD record
ord-be898c061fb349b5bbc2b1c06b2dd616
Source dataset
uspto-grants-1977_01
Patent number
US04005099

Reaction notes

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