HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Methoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Methoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea | HCID 21269584 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-Methoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea hydrochloride | HCID 21269583 | — |
Reaction Steps
1-Methoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea (3.0 g) was dissolved in the minimum quantity of ethanol and the solution treated with diethyl ether (300 ml), followed by an excess of a saturated solution of hydrogen chloride in diethyl ether. The resultant solid was filtered off and recrystallised from ethanol to give 1-methoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea hydrochloride (2.8 g) m.p. 187°-188° C. (with decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04005217 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-9dad1af15ad0463db35b4d3ebd2659f5 |
| Source note | uspto-grants-1977_01 |