反应详情

1-Methoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea (3.0 g) was dissolved in the minimum quantity of ethanol and the solution treated with diethyl ether (300 ml), followed by an excess of a saturated solution of hydrogen chloride in diethyl ether. The resultant solid was filtered off and recrystallised from ethanol to give 1-methoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea hydrochloride (2.8 g) m.p. 187°-188° C. (with decomposition).

1. filtrationThe resultant solid was filtered off
2. customrecrystallised from ethanol