HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 1-Ethoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 1-Ethoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea | HCID 21482982 | — |
| Solvent | Ethanol | HCID 702 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 1-Ethoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea hydrochloride | HCID 21483063 | — |
Reaction Steps
1-Ethoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea (5.0 g) was dissolved in the minimum quantity of ethanol and the solution treated with diethyl ether (500 ml), followed by a saturated solution of hydrogen chloride in diethyl ether. The resultant solid was filtered off and recrystallised from ethanol/diethyl ether to give 1-ethoxycarbonyl-3-(2-dimethylaminoacetamidophenyl)thiourea hydrochloride (4.3 g), m.p. 178°-180° C. (with decomposition).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04005217 |
| Source dataset | uspto-grants-1977_01 |
| ORD ID | ord-eb1be748e62f42b9af18701679b19d15 |
| Source note | uspto-grants-1977_01 |