HRID1415674

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID18423308

未命名化合物

结构：CC(C)(C)OC(=O)c1ccc(C(=O)NC(C(=N)N)C(=O)O)cc1

HCID86754082

未命名化合物

PRODUCTS

生成物

结构：CC(C)(C)OC(=O)c1ccc(C(=O)NC(C(=N)N)C(=O)N2CCN(CC(=O)OCc3ccccc3)CC2)cc1

HCID86754081

未命名化合物

PROCEDURE

实验过程

4-(4-Amidinobenzamidoacetyl)piperazin-1-ylacetic acid, FAB 348, is obtained analogously from 4-(4-BOC-amidinobenzamidoacetyl)piperazin-1-ylacetic acid (FAB 448; obtainable by condensing 4-BOC-amidinobenzamidoacetic acid with benzyl piperazin-1-ylacetate to give benzyl 4-(4-BOC-amidinobenzamidoacetyl)piperazin-1-ylacetate and hydrogenolyzing the benzyl ester group).

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-8d7bca2b674147d3962ca1e32a2d007b
来源数据集: uspto-grants-1999_06
DOI: 10.6084/m9.figshare.5104873.v1
专利: US05908843
来源说明: uspto-grants-1999_06

反应 SMILES

[C:1]([C:8]1[CH:23]=[CH:22][C:11]([C:12]([NH:14][CH:15]([C:19](=[NH:21])[NH2:20])[C:16]([OH:18])=O)=[O:13])=[CH:10][CH:9]=1)([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].[N:24]1([CH2:30][C:31]([O:33][CH2:34][C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)=[O:32])[CH2:29][CH2:28][NH:27][CH2:26][CH2:25]1>>[C:1]([C:8]1[CH:9]=[CH:10][C:11]([C:12]([NH:14][CH:15]([C:19](=[NH:21])[NH2:20])[C:16]([N:27]2[CH2:26][CH2:25][N:24]([CH2:30][C:31]([O:33][CH2:34][C:35]3[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=3)=[O:32])[CH2:29][CH2:28]2)=[O:18])=[O:13])=[CH:22][CH:23]=1)([O:3][C:4]([CH3:7])([CH3:5])[CH3:6])=[O:2]