Triethylamine → HCID 10589770, compound

Participants

Reaction Conditions

Reaction Steps

2-Bromoethyl chloroformate (5.6 mL, 50 mmol) was added to a stirred suspension of bis(2-chloroethyl)amine hydrochloride (9.8 g, 55 mmol) in 250 mL of dry dichloromethane at 0-5° C. under argon over 2 min followed by 28 mL (200 mmol) of triethylamine over 20 min. The mixture was stirred at 5-10° C. for 3 h and at room temperature for 18 h, then suction filtered. The filtrate was concentrated in vacuo.

Provenance & Evidence